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pentobarbital will minimize the level or outcome of efavirenz by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Importance Unidentified.pentobarbital will lessen the level or outcome of celecoxib by influencing hepatic enzyme CYP2C9/ten metabolism. Slight/Importance Mysterious.buprenorphine subdermal implant and pentobarbital the two